University of California San Francisco

Shuvo Roy, PhD
Shuvo
Roy
PhD

Professor, Departments of Bioengineering & Therapeutic Sciences and Surgery
UCSF Schools of Pharmacy and Medicine
Engineering Lead, Surgical Innovations Program
Director, Biodesign Laboratory
UCSF Faculty Director, UC Berkeley-UCSF Master of Translational Medicine (MTM) Program
Technical Director, The Kidney Project

 

Address

1700 4th Street, #203A
San Francisco, CA 94158
United States

Email: [email protected]
Phone: 415-514-9666
Fax: 415-514-9656

Biography

Shuvo Roy, PhD, is a translational bioengineer focusing on the development of medical devices to address unmet clinical needs through strong collaboration and a multidisciplinary approach.

Dr. Roy is a professor at the University of California, San Francisco in the Department of Bioengineering and Therapeutic Sciences (BTS), a joint department of the UCSF Schools of Pharmacy and Medicine, and is a faculty affiliate of the California Institute for Quantitative Biosciences (QB3). He is the director of the Biodesign Laboratory located on the Mission Bay campus. In addition, he serves as the Technical Director of The Kidney Project and is a founding member of the UCSF Pediatric Device Consortium. Dr. Roy is the Faculty Director of the joint UCSF-UC Berkeley Master of Translational Medicine (MTM) program. He has developed and currently teaches a course focused on medical device development and commercialization issues. He is the author of more than 100 publications and co-author of five book chapters, and holds multiple patents for device developments.

Before joining UCSF in 2008, Dr. Roy co-directed the BioMEMS Laboratory in the Department of Biomedical Engineering at Cleveland Clinic in Cleveland, Ohio, focusing on clinical applications of MEMS. In 1992 he earned a BS degree, magna cum laude, for triple majors in physics, mathematics, and computer science, from Mount Union College in Alliance, Ohio. In 1995, he earned an MS in electrical engineering and applied physics and, in 2001, he earned a PhD in electrical engineering and computer science, both from Case Western Reserve University in Cleveland, Ohio.

He is the recipient of a Top 40 under 40 award by Crain’s Cleveland Business in 1999 and the Clinical Translation Award at the 2nd Annual BioMEMS and Biomedical Nanotechnology World 2001 meeting. In 2003, Dr. Roy was selected as a recipient of the TR100, which features the world’s 100 Top Young Innovators as selected by Technology Review, the Massachusetts Institute of Technology’s Magazine of Innovation. In 2004, he was presented with a NASA Group Achievement Award for his work on harsh environment MEMS. In 2005, Dr. Roy was named as a Who’s Who in Biotechnology by Crain’s Cleveland Business. In 2005 and 2007, he was recognized as a Cleveland Clinic Innovator. In 2009, he was nominated for the Biotechnology Industry Organization's Biotech Humanitarian Award, which is given in recognition of an individual who has used biotechnology to unlock its potential to improve the earth. In 2012, he was presented the Rising Star Award by BayBio Pantheon, and in that same year, he received the Innovation Pathway 2.0 Award from the Food and Drug Administration (FDA). More recently, he was recognized as a Fellow by the American Institute of Medical and Biological Engineering (AIMBE). He is the recipient of the KidneyX Redesign Dialysis Phase 1 Prize, KidneyX Redesign Dialysis Phase 2 Prize, the KidneyX Artificial Kidney Phase 1 Prize, and most recently, the KidneyX Artificial Kidney Phase 2 Prize.

Videos

Awards & Honors

Award Conferred By Date
Medal of Excellence - Breakthrough Innovations American Association of Kidney Patients 2022
Presidential Volunteer Service Award - Gold Medal U.S. Presidential Volunteer Service awards - nomination by American Association of Kidney Patients 2022
Commendation for Exceptional Volunteerism and University Service Organized, Rapid, Intelligent Fabrication (ORIF) Team for UCSF's COVD-19 Pandemic Response 2021
KidneyX Artificial Kidney Phase 1, Winner US Dept. of Health and Human Services & American Society of Nephrology 2021
KidneyX Redesign Dialysis Phase 2, Winner US Dept. of Health and Human Services & American Society of Nephrology 2020
Dean's Apple Award - Outstanding Efforts and Commitment to Pharmacy Education UCSF PharmD Degree Program 2019
KidneyX Redesign Dialysis Phase 1, Winner US Dept. of Health and Human Services & American Society of Nephrology 2019
Elected Fellow of American Institute of Medical and Biological Engineering (AIMBE) American Institute of Medical and Biological Engineering (AIMBE) 2017
La Renon TANKER foundation For the Sake of Honour Award Tamilnad Kidney Research Foundation (TANKER) 2017
Annual Home Dialyzors United (HDU) Chris Blagg Award Home Dialyzors United (HDU) 2016
Innovation in Regulatory Science, Finalist Burroughs Wellcome Fund 2015
UCSF Outstanding Faculty Mentorship Award, Finalist UCSF 2014
Fellow Applied Innovation Institute 2013
Requested Nominator Heinz Awards 2013
Rising Star Award BayBio Pantheon 2012
Innovation Pathway 2.0 Award Food and Drug Administration (FDA) 2012
UCSF Outstanding Faculty Mentorship Award, Finalist University of California, San Francisco 2012
mHealth Alliance Award Vodafone Americas Foundation 2011
Images of the Year Selection Biomaterials Journal 2009
Biotech Humanitarian Award Finalist Biotechnology Industry Organization 2009
Thomas G. Orr Memorial Lectureship Southwestern Surgical Congress 2008
Cleveland Clinic Innovator Award Cleveland Clinic 2007
Mentor Recognition Award Cleveland Clinic Science Internship Program 2006
Cleveland Clinic Innovator Award Cleveland Clinic 2005
Who's Who in Biotechnology Crain's Cleveland Business 2005
Ribbon Award, Outstanding Symposium Paper, MRS Fall Meeting Materials Research Society 2004
NASA Group Achievement Award, Harsh Environment MEMS NASA 2004
MIT TR100 Award, Top 100 Young Innovators Technology Review Magazine 2003
Clinical Translation Award BioMEMS and Biomedical Nanotechnology World Meeting 2001
Top 40 Under 40 Crain's Cleveland Business 1999
Ruth Barber Moon Graduate Student Award Case Western Reserve University 1998
Senior Physics Prize Mount Union College 1992
William and Burdella Carl Mathematics Award Mount Union College 1989

Education

Institution Degree Dept or School End Date
Case Western Reserve University PhD Electrical Engineering and Computer Science 2001
Case Western Reserve University MS Electrical Engineering and Applied Physics 1995
Mount Union College BS Physics, Mathematics, Computer Science 1992

Clinical Trials

  1. Blood Flow Effects on Silicon Substrates (NCT03241667)
    Related Conditions: End Stage Renal Disease| Start Date: | End Date:

Program Affiliations

UCSF - UC Berkeley Joint Graduate Group in Bioengineering
Pharmaceutical Sciences and Pharmacogenomics Graduate Program (PSPG)
UC Berkeley - UCSF Master of Translational Medicine (MTM) Program California Institute for Quantitative Biosciences (QB3)

Grants and Funding

  • Biodevice Innovation Training Program | NIH | 2017-05-15 - 2022-04-30 | Role: Co-Principal Investigator
  • Implantable Bio-Artificial Pancreas (iBAP) | NIH | 2017-09-26 - 2021-06-30 | Role: Principal Investigator
  • Building an Implantable Artificial Kidney | NIH | 2015-09-30 - 2021-06-30 | Role: Principal Investigator
  • Biocompatibility of Implantable Renal Replacement Devices | NIH | 2012-05-01 - 2017-04-30 | Role: Principal Investigator
  • Miniaturized Implantable Renal Assist Device for Total Renal Replacement Therapy | NIH | 2007-09-30 - 2011-08-31 | Role: Principal Investigator
  • Microneedle Array for Catheter Drug Delivery | NIH | 2003-09-12 - 2006-08-31 | Role: Principal Investigator

Research Narrative

Chronic kidney failure threatens about half a million people in the U.S. alone. Donated kidneys can restore health, but they are in are in short supply.  As a result, some 350,000 people with failing kidneys are tethered to dialysis machines several days a week – a tiring, uncomfortable and expensive treatment, and one that falls far short of performing a normal kidney’s functions. Shuvo Roy, a professor in the UCSF Department of Bioengineering and Therapeutic Sciences, and his colleagues are developing an implantable, fully functional artificial kidney.  

Research projects include:

  • Development of an artificial kidney
  • Development of an intravascular bioreactor for islet therapy in Type 1 diabetes patients
  • Investigation into covalent attachment of self-assembled monolayer films to enhance biocompatibility of implanted devices
  • Resorbable electronics for tissue monitoring and stimulation, and dataloggers for patient monitoring
  • Development of compact hemofilters for renal replacement therapy
  • Wireless sensing systems for load measurement
  • Focused ultrasound transducers for minimally invasive imaging and therapy

Research Interests

Therapeutics

Bioengineering

Medical Devices

Microelectromechanical Systems

BioMEMS

Sensors

Transducers

Biocompatibility

Artificial Organs

Microtextured Substrates

Renal Replacement

Tissue Engineering

Nanotechnology

Artificial Kidney

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 120
  1. What is the feasibility of a clinical-scale and anticoagulation-free artificial placenta device?
    Blauvelt D, Roy S| | PubMed
  2. An arteriovenous mock circulatory loop and accompanying bond graph model for in vitro study of peripheral intravascular bioartificial organs.
    Moyer JC, Chivukula VK, Taheri-Tehrani P, Sandhu S, Blaha C, Fissell WH, Roy S| | PubMed
  3. Patient Preference Trade-offs for Next-Generation Kidney Replacement Therapies.
    Wilson L, Gress AF, Frassetto L, Sarathy H, Gress EA, Fissell WH, Roy S| | PubMed
  4. Renal Embolization-Induced Uremic Swine Model for Assessment of Next-Generation Implantable Hemodialyzers.
    Moyer J, Wilson MW, Sorrentino TA, Santandreu A, Chen C, Hu D, Kerdok A, Porock E, Wright N, Ly J, Blaha C, Frassetto LA, Fissell WH, Vartanian SM, Roy S| | PubMed
  5. Feasibility of an implantable bioreactor for renal cell therapy using silicon nanopore membranes.
    Kim EJ, Chen C, Gologorsky R, Santandreu A, Torres A, Wright N, Goodin MS, Moyer J, Chui BW, Blaha C, Brakeman P, Vartanian S, Tang Q, David Humes H, Fissell WH, Roy S| | PubMed
  6. Characterization of human islet function in a convection-driven intravascular bioartificial pancreas.
    Santandreu AG, Taheri-Tehrani P, Feinberg B, Torres A, Blaha C, Shaheen R, Moyer J, Wright N, Szot GL, Fissell WH, Vartanian S, Posselt A, Roy S| | PubMed
  7. Silicon membranes for extracorporeal life support: a comparison of design and fabrication methodologies.
    Blauvelt DG, Chui BW, Higgins NC, Baltazar FJ, Roy S| | PubMed
  8. Inhibition of Transforming Growth Factor-β Improves Primary Renal Tubule Cell Differentiation in Long-Term Culture.
    Hunter K, Larsen JA, Love HD, Evans RC, Roy S, Zent R, Harris RC, Wilson MH, Fissell WH| | PubMed
  9. Functionalizing Polyacrylamide Hydrogels for Renal Cell Culture Under Fluid Shear Stress.
    Love H, Evans R, Hunter K, Roy S, Fissell WH| | PubMed
  10. Wearable and implantable artificial kidney devices for end-stage kidney disease treatment: Current status and review.
    Groth T, Stegmayr BG, Ash SR, Kuchinka J, Wieringa FP, Fissell WH, Roy S| | PubMed
  11. The Advancing American Kidney Health Initiative: The Challenge of Overcoming the Status Quo.
    Conway PT, Gedney N, Roy S, Fissell WH| | PubMed
  12. Superporous agarose scaffolds for encapsulation of adult human islets and human stem-cell-derived β cells for intravascular bioartificial pancreas applications.
    Shaheen R, Gurlin RE, Gologorsky R, Blaha C, Munnangi P, Santandreu A, Torres A, Carnese P, Nair GG, Szot G, Fissell WH, Hebrok M, Roy S| | PubMed
  13. Opportunities for Regulatory Changes to Promote Pediatric Device Innovation in the United States: Joint Recommendations From Pediatric Innovator Roundtables.
    Sanger T, Chang A, Feaster W, Taraman S, Afari N, Beauregard D, Dethlefs B, Ghere T, Kabeer M, Tolomiczenko G, Billig M, Brophy J, Eskandanian K, Espinoza J, Farrugia S, Harrison M, Horvat C, Hoyen C, Koh C, Komiyama A, Nelson K, Kulkarni O, Levy R, Maher K, O'Donnell M, Ponsky T, Richmond F, Richter J, Roy S, Samir S, Suresh S, Stallworth C, Thekkedath U, Toman K, Wall J, West L, Wolff D| | PubMed
  14. Use of Ballistocardiography to Monitor Cardiovascular Hemodynamics in Preeclampsia.
    Quesada O, Shandhi MMH, Beach S, Dowling S, Tandon D, Heller J, Etemadi M, Roy S, Gonzalez Velez JM, Inan OT, Klein L| | PubMed
  15. Advances in extracorporeal membrane oxygenator design for artificial placenta technology.
    Blauvelt DG, Abada EN, Oishi P, Roy S| | PubMed
  16. Metformin and Inhibition of Transforming Growth Factor-Beta Stimulate In Vitro Transport in Primary Renal Tubule Cells.
    Love H, Evans R, Humes HD, Roy S, Zent R, Harris R, Wilson M, Fissell WH| | PubMed
  17. Treating the kidneys - a new era in the United States (and beyond).
    Fissell WH, Roy S| | PubMed
  18. Ambulatory Hemodialysis-Technology Landscape and Potential for Patient-Centered Treatment.
    Hojs N, Fissell WH, Roy S| | PubMed
  19. Endovascular Ion Exchange Chemofiltration Device Reduces Off-Target Doxorubicin Exposure in a Hepatic Intra-arterial Chemotherapy Model.
    Yee C, McCoy D, Yu J, Losey A, Jordan C, Moore T, Stillson C, Oh HJ, Kilbride B, Roy S, Patel A, Wilson MW, Hetts SW, ChemoFilter Consortium| | PubMed
  20. Genome Engineering Renal Epithelial Cells for Enhanced Volume Transport Function.
    Wilson MH, Veach RA, Luo W, Welch RC, Roy S, Fissell WH| | PubMed
  21. Ultrafiltration for management of fluid overload in patients with heart failure.
    Gologorsky RC, Roy S| | PubMed
  22. Substrate Elasticity Governs Differentiation of Renal Tubule Cells in Prolonged Culture.
    Love HD, Ao M, Jorgensen S, Swearingen L, Ferrell N, Evans R, Gewin L, Harris RC, Zent R, Roy S, Fissell WH| | PubMed
  23. In Vitro models for thrombogenicity testing of blood-recirculating medical devices.
    Sarode DN, Roy S| | PubMed
  24. Application of physiological shear stress to renal tubular epithelial cells.
    Ferrell N, Sandoval RM, Molitoris BA, Brakeman P, Roy S, Fissell WH| | PubMed
  25. Compliance monitoring via a Bluetooth-enabled retainer: A prospective clinical pilot study.
    Castle E, Chung P, Behfar MH, Chen M, Gao J, Chiu N, Nelson G, Roy S, Oberoi S| | PubMed
  26. Apical Shear Stress Enhanced Organic Cation Transport in Human OCT2/MATE1-Transfected Madin-Darby Canine Kidney Cells Involves Ciliary Sensing.
    Jayagopal A, Brakeman PR, Soler P, Ferrell N, Fissell W, Kroetz DL, Roy S| | PubMed
  27. In vitro and in vivo hemocompatibility assessment of ultrathin sulfobetaine polymer coatings for silicon-based implants.
    Iqbal Z, Kim S, Moyer J, Moses W, Abada E, Wright N, Kim EJ, Park J, Fissell WH, Vartanian S, Roy S| | PubMed
  28. Orbital Shear Stress Regulates Differentiation and Barrier Function of Primary Renal Tubular Epithelial Cells.
    Ferrell N, Cheng J, Miao S, Roy S, Fissell WH| | PubMed
  29. Acoustic Methods for Pulmonary Diagnosis.
    Rao A, Huynh E, Royston TJ, Kornblith A, Roy S| | PubMed
  30. Evaluation of silicon membranes for extracorporeal membrane oxygenation (ECMO).
    Abada EN, Feinberg BJ, Roy S| | PubMed
  31. Innovations in Wearable and Implantable Artificial Kidneys.
    Salani M, Roy S, Fissell WH| | PubMed
  32. Improved Detection of Lung Fluid With Standardized Acoustic Stimulation of the Chest.
    Rao A, Chu S, Batlivala N, Zetumer S, Roy S| | PubMed
  33. Tabla: A Proof-of-Concept Auscultatory Percussion Device for Low-Cost Pneumonia Detection.
    Rao A, Ruiz J, Bao C, Roy S| | PubMed
  34. Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges.
    Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M| | PubMed
  35. Combined In Silico and In Vitro Approach Predicts Low Wall Shear Stress Regions in a Hemofilter that Correlate with Thrombus Formation In Vivo.
    Buck AKW, Groszek JJ, Colvin DC, Keller SB, Kensinger C, Forbes R, Karp S, Williams P, Roy S, Fissell WH| | PubMed
  36. Original article submission: Platelet stress accumulation analysis to predict thrombogenicity of an artificial kidney.
    Buck AKW, Goebel SG, Goodin MS, Wright NJ, Groszek JJ, Moyer J, Singh S, Bluestein D, Fissell WH, Roy S| | PubMed
  37. Novel Wearable Seismocardiography and Machine Learning Algorithms Can Assess Clinical Status of Heart Failure Patients.
    Inan OT, Baran Pouyan M, Javaid AQ, Dowling S, Etemadi M, Dorier A, Heller JA, Bicen AO, Roy S, De Marco T, Klein L| | PubMed
  38. Slit pores preferred over cylindrical pores for high selectivity in biomolecular filtration.
    Feinberg BJ, Hsiao JC, Park J, Zydney AL, Fissell WH, Roy S| | PubMed
  39. Sterilization effects on ultrathin film polymer coatings for silicon-based implantable medical devices.
    Iqbal Z, Moses W, Kim S, Kim EJ, Fissell WH, Roy S| | PubMed
  40. Silicon Micropore-Based Parallel Plate Membrane Oxygenator.
    Dharia A, Abada E, Feinberg B, Yeager T, Moses W, Park J, Blaha C, Wright N, Padilla B, Roy S| | PubMed
  41. Correction: An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport.
    Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S| | PubMed
  42. An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport.
    Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S| | PubMed
  43. A distributed solute model: an extended two-pore model with application to the glomerular sieving of Ficoll.
    Öberg CM, Groszek JJ, Roy S, Fissell WH, Rippe B| | PubMed
  44. Silicon nanoporous membranes as a rigorous platform for validation of biomolecular transport models.
    Feinberg BJ, Hsiao JC, Park J, Zydney AL, Fissell WH, Roy S| | PubMed
  45. Glucose-Stimulated Insulin Response of Silicon Nanopore-Immunoprotected Islets under Convective Transport.
    Song S, Yeung R, Park J, Posselt AM, Desai TA, Tang Q, Roy S| | PubMed
  46. Evolution of Gas Permeable Membranes for Extracorporeal Membrane Oxygenation.
    Yeager T, Roy S| | PubMed
  47. A modular microfluidic bioreactor with improved throughput for evaluation of polarized renal epithelial cells.
    Brakeman P, Miao S, Cheng J, Lee CZ, Roy S, Fissell WH, Ferrell N| | PubMed
  48. Quantifying and Reducing Motion Artifacts in Wearable Seismocardiogram Measurements During Walking to Assess Left Ventricular Health.
    Javaid AQ, Ashouri H, Dorier A, Etemadi M, Heller JA, Roy S, Inan OT| | PubMed
  49. Inductive passive sensor for intraparenchymal and intraventricular monitoring of intracranial pressure.
    Behfar MH, Abada E, Sydanheimo L, Goldman K, Fleischman AJ, Gupta N, Ukkonen L, Roy S| | PubMed
  50. Diffusive Silicon Nanopore Membranes for Hemodialysis Applications.
    Kim S, Feinberg B, Kant R, Chui B, Goldman K, Park J, Moses W, Blaha C, Iqbal Z, Chow C, Wright N, Fissell WH, Zydney A, Roy S| | PubMed
  51. First Implantation of Silicon Nanopore Membrane Hemofilters.
    Kensinger C, Karp S, Kant R, Chui BW, Goldman K, Yeager T, Gould ER, Buck A, Laneve DC, Groszek JJ, Roy S, Fissell WH| | PubMed
  52. Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport.
    Song S, Faleo G, Yeung R, Kant R, Posselt AM, Desai TA, Tang Q, Roy S| | PubMed
  53. Preliminary Diffusive Clearance of Silicon Nanopore Membranes in a Parallel Plate Configuration for Renal Replacement Therapy.
    Kim S, Heller J, Iqbal Z, Kant R, Kim EJ, Durack J, Saeed M, Do L, Hetts S, Wilson M, Brakeman P, Fissell WH, Roy S| | PubMed
  54. Progress and challenges in macroencapsulation approaches for type 1 diabetes (T1D) treatment: Cells, biomaterials, and devices.
    Song S, Roy S| | PubMed
  55. MyPectus: First-in-human pilot study of remote compliance monitoring of teens using dynamic compression bracing to correct pectus carinatum.
    Harrison B, Stern L, Chung P, Etemadi M, Kwiat D, Roy S, Harrison MR, Martinez-Ferro M| | PubMed
  56. Corrigendum to: Biocompatibility evaluation of a thermoplastic rubber for wireless telemetric intracranial pressure sensor coating.
    Yang J, Charif AC, Puskas JE, Phillips H, Shanahan KJ, Garsed J, Fleischman A, Goldman K, Roy S, Luebbers MT, Dombrowski SM, Luciano MG| | PubMed
  57. A Wearable Patch to Enable Long-Term Monitoring of Environmental, Activity and Hemodynamics Variables.
    Etemadi M, Inan OT, Heller JA, Hersek S, Klein L, Roy S| | PubMed
  58. Impedance sensing device enables early detection of pressure ulcers in vivo.
    Swisher SL, Lin MC, Liao A, Leeflang EJ, Khan Y, Pavinatto FJ, Mann K, Naujokas A, Young D, Roy S, Harrison MR, Arias AC, Subramanian V, Maharbiz MM| | PubMed
  59. The synergistic effect of micro-topography and biochemical culture environment to promote angiogenesis and osteogenic differentiation of human mesenchymal stem cells.
    Song S, Kim EJ, Bahney CS, Miclau T, Marcucio R, Roy S| | PubMed
  60. Biocompatibility evaluation of a thermoplastic rubber for wireless telemetric intracranial pressure sensor coating.
    Yang J, Charif AC, Puskas JE, Phillips H, Shanahan KJ, Garsed J, Fleischman A, Goldman K, Roy S, Luebbers MT, Dombrowski SM, Luciano MG| | PubMed
  61. Current strategies and challenges in engineering a bioartificial kidney.
    Kim S, Fissell WH, Humes DH, Roy S| | PubMed
  62. Impedance sensing device for monitoring ulcer healing in human patients.
    Liao A, Lin MC, Ritz LC, Swisher SL, Ni D, Mann K, Khan Y, Roy S, Harrison MR, Arias AC, Subramanian V, Young D, Maharbiz MM| | PubMed
  63. Toward continuous, noninvasive assessment of ventricular function and hemodynamics: wearable ballistocardiography.
    Wiens AD, Etemadi M, Roy S, Klein L, Inan OT| | PubMed
  64. Rapid and low-cost prototyping of medical devices using 3D printed molds for liquid injection molding.
    Chung P, Heller JA, Etemadi M, Ottoson PE, Liu JA, Rand L, Roy S| | PubMed
  65. Imaging assessment of a portable hemodialysis device: detection of possible failure modes and monitoring of functional performance.
    Olorunsola OG, Kim SH, Chang R, Kuo YC, Hetts SW, Heller A, Kant R, Saeed M, Fissell WH, Roy S, Wilson MW| | PubMed
  66. Miniaturizing RFID for magnamosis.
    Jiang H, Chen S, Kish S, Loh L, Zhang J, Zhang X, Kwiat D, Harrison M, Roy S| | PubMed
  67. Tracking clinical status for heart failure patients using ballistocardiography and electrocardiography signal features.
    Etemadi M, Hersek S, Tseng JM, Rabbani N, Heller JA, Roy S, Klein L, Inan OT| | PubMed
  68. Wearable ballistocardiography: preliminary methods for mapping surface vibration measurements to whole body forces.
    Wiens A, Etemadi M, Klein L, Roy S, Inan OT| | PubMed
  69. Microelectromechanical systems and nephrology: the next frontier in renal replacement technology.
    Kim S, Roy S| | PubMed
  70. A low-frequency versatile wireless power transfer technology for biomedical implants.
    Jiang H, Zhang J, Lan D, Liou S, Shahnasser H, Fechter R, Hirose S, Harrison M, Roy S| | PubMed
  71. Towards BirthAlert--A Clinical Device Intended for Early Preterm Birth Detection.
    Etemadi M, Chung P, Heller JA, Liu JA, Rand L, Roy S| | PubMed
  72. Response of bone marrow derived connective tissue progenitor cell morphology and proliferation on geometrically modulated microtextured substrates.
    Kim EJ, Fleischman AJ, Muschler GF, Roy S| | PubMed
  73. The bioartificial kidney: current status and future promise.
    Humes HD, Buffington D, Westover AJ, Roy S, Fissell WH| | PubMed
  74. Achieving more frequent and longer dialysis for the majority: wearable dialysis and implantable artificial kidney devices.
    Fissell WH, Roy S, Davenport A| | PubMed
  75. Fabric-based pressure sensor array for decubitus ulcer monitoring.
    Chung P, Rowe A, Etemadi M, Lee H, Roy S| | PubMed
  76. Novel device to trend impedance and fluorescence of the cervix for preterm birth detection.
    Etemadi M, Chung P, Heller JA, Liu J, Grossman-Kahn R, Rand L, Roy S| | PubMed
  77. Implantable ultra-low pulmonary pressure monitoring system for fetal surgery.
    Etemadi M, Heller JA, Schecter SC, Shue EH, Miniati D, Roy S| | PubMed
  78. A feed-forward controlled AC-DC boost converter for biomedical implants.
    Jiang H, Lan D, Lin D, Zhang J, Liou S, Shahnasser H, Shen M, Harrison M, Roy S| | PubMed
  79. Dynamic tracheal occlusion improves lung morphometrics and function in the fetal lamb model of congenital diaphragmatic hernia.
    Jelin EB, Etemadi M, Encinas J, Schecter SC, Chapin C, Wu J, Guevara-Gallardo S, Nijagal A, Gonzales KD, Ferrier WT, Roy S, Miniati D| | PubMed
  80. Hemocompatibility of silicon-based substrates for biomedical implant applications.
    Muthusubramaniam L, Lowe R, Fissell WH, Li L, Marchant RE, Desai TA, Roy S| | PubMed
  81. Anti-biofouling Sulfobetaine Polymer Thin Films on Silicon and Silicon Nanopore Membranes.
    Li L, Marchant RE, Dubnisheva A, Roy S, Fissell WH| | PubMed
  82. The Responsivity of a Miniaturized Passive Implantable Wireless Pressure Sensor.
    Jiang H, Lan D, Goldman K, Etemadi M, Shahnasser H, Roy S| | PubMed
  83. A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells.
    Ferrell N, Desai RR, Fleischman AJ, Roy S, Humes HD, Fissell WH| | PubMed
  84. Basal lamina secreted by MDCK cells has size- and charge-selective properties.
    Ferrell N, Groszek J, Li L, Smith R, Butler RS, Zorman CA, Roy S, Fissell WH| | PubMed
  85. Design and analysis of MEMS based PVDF ultrasonic transducers for vascular imaging.
    Chandrana C, Talman J, Pan T, Roy S, Fleischman A| | PubMed
  86. Molecular conformation and filtration properties of anionic Ficoll.
    Groszek J, Li L, Ferrell N, Smith R, Zorman CA, Hofmann CL, Roy S, Fissell WH| | PubMed
  87. Silicon induces minimal thromboinflammatory response during 28-day intravascular implant testing.
    Melvin ME, Fissell WH, Roy S, Brown DL| | PubMed
  88. Demonstration of second-harmonic IVUS feasibility with focused broadband miniature transducers.
    Chandrana C, Kharin N, Vince G, Roy S, Fleischman A| | PubMed
  89. Characterizing the surface charge of synthetic nanomembranes by the streaming potential method.
    Datta S, Conlisk AT, Kanani DM, Zydney AL, Fissell WH, Roy S| | PubMed
  90. Permeability - Selectivity Analysis for Ultrafiltration: Effect of Pore Geometry.
    Kanani DM, Fissell WH, Roy S, Dubnisheva A, Fleischman A, Zydney AL| | PubMed
  91. A high-power versatile wireless power transfer for biomedical implants.
    Jiang H, Zhang JM, Liou SS, Fechter R, Hirose S, Harrison M, Roy S| | PubMed
  92. The implantable artificial kidney.
    Fissell WH, Roy S| | PubMed
  93. Modulating human connective tissue progenitor cell behavior on cellulose acetate scaffolds by surface microtextures.
    Kim EJ, Boehm CA, Fleischman AJ, Muschler GF, Kostov YV, Roy S| | PubMed
  94. Solute partitioning and filtration by extracellular matrices.
    Fissell WH, Hofmann CL, Ferrell N, Schnell L, Dubnisheva A, Zydney AL, Yurchenco PD, Roy S| | PubMed
  95. Post microtextures accelerate cell proliferation and osteogenesis.
    Kim EJ, Boehm CA, Mata A, Fleischman AJ, Muschler GF, Roy S| | PubMed
  96. A three-dimensional scaffold with precise micro-architecture and surface micro-textures.
    Mata A, Kim EJ, Boehm CA, Fleischman AJ, Muschler GF, Roy S| | PubMed
  97. Biomolecular transport through hemofiltration membranes.
    Conlisk AT, Datta S, Fissell WH, Roy S| | PubMed
  98. High-Performance Silicon Nanopore Hemofiltration Membranes.
    Fissell WH, Dubnisheva A, Eldridge AN, Fleischman AJ, Zydney AL, Roy S| | PubMed
  99. Development of multistage magnetic deposition microscopy.
    Nath P, Strelnik J, Vasanji A, Moore LR, Williams PS, Zborowski M, Roy S, Fleischman AJ| | PubMed
  100. Basic Science Symposium II: MEMS Technology.
    Roy S, Fleischman A, Benzel EC, Cameron BD, Ferrara L, Goel VK| | PubMed
  101. In Vivo Assessment of Bone Graft/Endplate Contact Pressure in a Caprine Interbody Pseudarthrosis Model: A Preliminary Biomechanical Characterization of the Fusion Process for the Development of a Microelectromechanical Systems (MEMS) Biosensor.
    Ferrara LA, Gordon I, Schlenk R, Coquillette M, Fleischman AJ, Roy S, Togawa D, Bauer TW, Benzel EC| | PubMed
  102. A preliminary biomechanical evaluation in a simulated spinal fusion model. Laboratory investigation.
    Ferrara LA, Gordon I, Coquillette M, Milks R, Fleischman AJ, Roy S, Goel VK, Benzel EC| | PubMed
  103. Quantification of magnetic susceptibility in several strains of Bacillus spores: implications for separation and detection.
    Melnik K, Sun J, Fleischman A, Roy S, Zborowski M, Chalmers JJ| | PubMed
  104. Ficoll is not a rigid sphere.
    Fissell WH, Manley S, Dubnisheva A, Glass J, Magistrelli J, Eldridge AN, Fleischman AJ, Zydney AL, Roy S| | PubMed
  105. Development of continuous implantable renal replacement: past and future.
    Fissell WH, Fleischman AJ, Humes HD, Roy S| | PubMed
  106. Connective tissue progenitor cell growth characteristics on textured substrates.
    Mata A, Boehm C, Fleischman AJ, Muschler GF, Roy S| | PubMed
  107. Differentiated growth of human renal tubule cells on thin-film and nanostructured materials.
    Fissell WH, Manley S, Westover A, Humes HD, Fleischman AJ, Roy S| | PubMed
  108. Electrochemical detection and characterization of proteins.
    Smiechowski MF, Lvovich VF, Roy S, Fleischman A, Fissell WH, Riga AT| | PubMed
  109. Continuous flow magnetic cell fractionation based on antigen expression level.
    Schneider T, Moore LR, Jing Y, Haam S, Williams PS, Fleischman AJ, Roy S, Chalmers JJ, Zborowski M| | PubMed
  110. Orthogonal-coil RF probe for implantable passive sensors.
    Talman JR, Fleischman AJ, Roy S| | PubMed
  111. Evaluation of silicon nanoporous membranes and ECM-based microenvironments on neurosecretory cells.
    Lopez CA, Fleischman AJ, Roy S, Desai TA| | PubMed
  112. Spine biomechanics: fundamentals and future.
    Benzel EC, Kayanja M, Fleischman A, Roy S| | PubMed
  113. Characterization of polydimethylsiloxane (PDMS) properties for biomedical micro/nanosystems.
    Mata A, Fleischman AJ, Roy S| | PubMed
  114. A system for micro/nano fluidic flow diagnostics.
    Nath P, Roy S, Conlisk T, Fleischman AJ| | PubMed
  115. Micromachines in spine surgery.
    Benzel E, Ferrara L, Roy S, Fleischman A| | PubMed
  116. Osteoblast attachment to a textured surface in the absence of exogenous adhesion proteins.
    Mata A, Su X, Fleischman AJ, Roy S, Banks BA, Miller SK, Midura RJ| | PubMed
  117. Growth of connective tissue progenitor cells on microtextured polydimethylsiloxane surfaces.
    Mata A, Boehm C, Fleischman AJ, Muschler G, Roy S| | PubMed
  118. Analysis of connective tissue progenitor cell behavior on polydimethylsiloxane smooth and channel micro-textures.
    Mata A, Boehm C, Fleischman AJ, Muschler G, Roy S| | PubMed
  119. Evaluation of MEMS materials of construction for implantable medical devices.
    Kotzar G, Freas M, Abel P, Fleischman A, Roy S, Zorman C, Moran JM, Melzak J| | PubMed
  120. Biomaterials and implantable devices: discoveries in the spine surgery arena.
    Benzel EC, Ferrara LA, Roy S, Fleischman AJ| | PubMed